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Urological Conditions, Intimacy and Relationships

‘You in Urology’ is intended for people living with urological conditions (including bladder cancer, prostate cancer and overactive bladder) and their caregivers. The information provided by Astellas is for informational purposes only and is not meant to replace the advice of a healthcare professional.

 

This website was initiated and funded by Astellas Pharma Europe. All patient and healthcare organisations involved in the development of the platform received a fee for their time.

Intimacy and relationships

Some people with urological conditions may find sex more difficult or may not want to be intimate.1-6 Some people also experience difficult emotions that can affect their relationships. There are different reasons you might have these difficulties, depending on the condition you have.

 

Whatever the cause, we understand this may affect your relationship with your partner and how you feel about your body. It could also make meeting a new partner more daunting.

 

But having a urological condition doesn’t have to mean losing intimacy. Open communication, preparation and learning about what’s happening in your body can help you. There is support available for you when you need it.

It’s okay to ask for help

It’s important to recognise if changes in your relationships or sex life are affecting your quality of life. Speaking about sex, intimacy and relationships can be difficult for anyone. But speaking with your healthcare team, your partner or even your friends could help you work through any challenges you may be facing.

 

Your care should centre around you.

 

Sometimes knowing what to ask can help you find the support you need. This could be as simple as guidance on how to talk more honestly with your partner. For some people, there may also be options to address the underlying physical issues. The right type of support for you will depend on many factors. This includes your diagnosis, symptoms, stage of disease and personal preferences.

 

The main thing to remember is that you’re not alone, and you can still find ways to be intimate and maintain healthy relationships.

The “You in Urology” pan-urology panel talk about the impact of urological conditions on sex, intimacy and relationships.

How your diagnosis might affect physical intimacy

The ways different conditions might affect your ability and desire to have sex can be varied. But the overall impact on intimacy and relationships may be similar.

Overactive bladder (OAB), with or without incontinence, may affect your sex life. This is because for some men and women with OAB, it can reduce their sexual activity and enjoyment of sex.1,2 Up to 30% of women with OAB experience some sort of impact on sexual function.7 Erectile dysfunction and premature ejaculation are also common among men with OAB.8

Intimacy and cancer can be difficult to talk about. Bladder cancer can also affect your sex life and relationships in different ways. Some changes could be due to your symptoms or how you are feeling emotionally, and others happen because of treatment or surgery.4,9 For example, if your bladder cancer is more advanced or you’ve had your bladder removed (radical cystectomy), it can be more difficult to have sex.10

 

Men and women can have quite different experiences of living with bladder cancer and having sex. For women, it can reduce their desire to have sex.3 Some types of treatment can also shorten or narrow the vagina or damage the clitoris.3,11 This could make having sex feel different or more difficult.3 Up to 3 in 4 women with bladder cancer may have some kind of impact on their sex life.3

 

In men, some treatments can damage the nerves that control erections. Certain treatments may also make it difficult to ejaculate.4 Up to 8 in 10 men who have had their bladder removed report not being able to get or maintain an erection, and half of men with bladder cancer report ejaculation problems.4,10

Some people living with prostate cancer find their symptoms and emotional state can affect their sex life or relationships.6,9,12

 

Having your prostate removed (prostatectomy) can make it difficult to get or maintain an erection, due to nerve and blood vessel damage.6 When possible, surgeons may try to spare the nerves surrounding the prostate that control erections, but this depends on several factors.13 After a prostatectomy, it is not possible to ejaculate but it is possible to have an orgasm.5 Other treatments can also cause erectile dysfunction, changes in libido and ejaculation problems.5,6

 

This can make having sex after prostate cancer challenging. In a survey, three-quarters of men reported that their sex life was better before prostate cancer.14

More than just sex

It’s not just about sex and intimacy. How a person feels can also have an impact on relationships.15,16 For some people, their urological condition or treatments can:

  • Make them feel down or anxious18-20
  • Affect the way they feel about their body, causing negative body image20-22
  • Make it more difficult to be intimate with their partner17,20,22,23

This is normal when your body experiences changes or you have worries due to your condition or treatment, but it’s important to know what to expect. Talking openly can help you feel informed and work through these feelings and challenges.

Managing challenges with intimacy and relationships

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Intimacy and Relationships: Finding Your Way

Find out how you can manage the impact of your condition on your sex life.

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It’s Okay To Ask About Intimacy: Talking To Your Healthcare Team

Find out how to initiate conversations with your healthcare team, and what questions you might want to ask.

Useful websites

Patient organisations and the European Association of Urology (EAU) Patient Office provide many resources across a range of topics to support people with urological conditions.

 

Please note: The following links will take you to websites that are not owned or controlled by Astellas. Astellas is not responsible for the information or services on these sites. Astellas is not affiliated with and does not endorse any specific patient or healthcare organisation.

Logo of the European Association of Urology Patient Office.

The EAU Patient Office puts patients and patient advocates at the heart of clinical guideline development, awareness and patient education. It provides reliable information for patients with urological conditons.

Europa Uomo logo.

Europa Uomo represents 31 patient organisations in countries across Europe. They work with patient communities and healthcare professionals to improve diagnosis, treatment, support and quality of life for people affected by prostate cancer.

Fight Bladder Cancer logo.

Fight Bladder Cancer focuses on providing support for people affected by bladder cancer. It provides resources, information and tips for people at different stages – from diagnosis to post treatment. It also raises awareness, campaigns for more research and aims to drive change in health policy around bladder cancer care.

Associazione Palinuro logo.

Associazione PaLiNUro is an Italian organisation that aims to listen to, support and inform people affected by bladder cancer. In addition to sharing and confronting common problems, it wants to be a point of reference, defend the rights of the sick, help improve quality of life, be the voice of the sick person to those who “decide”, and actively involve the patient in their care.

Logo of the World Bladder Cancer Patient Coalition.

The World Bladder Cancer Patient Coalition represents 16 patient organisations from 13 different countries. It provides information on bladder cancer, can help you find local organisations, and offers a range of toolkits and resources. 

Logo of the World Federation of Incontinence and Pelvic Problems.

The World Federation of Incontinence and Pelvic Problems (WFIPP) is an organisation acting as a global platform for all people living with incontinence and pelvic floor dysfunction. It provides information, resources and support for people with incontinence and pelvic floor dysfunction, irrespective of the cause.

  1. Coyne, K.S., Sexton, C.C., Thompson, C., Kopp, Z.S., Milsom, I., & Kaplan, S.A. The Impact of OAB on Sexual Health in Men and Women: Results from EpiLUTS. The Journal of Sexual Medicine, 8[6]:1603–1615 (2011). https://doi.org/10.1111/j.1743-6109.2011.02250.x
  2. Sondka-Migdalska, J., Blaszcyzynski, P., Jablonowski, Z. (2024).   Sexual Dysfunction in Patients with Overactive Bladder Syndrome Treated with Botulinum Toxin. J. Clin. Med. 2024, 13, 5869. https://doi.org/10.3390/jcm13195869
  3. Martin, R., Renouf, T., Rigby, J., Hafeez, S., Thurairaja, R., Kumar, P., Cruickshank, S., & Van-Hemelrijck M. Female sexual function in bladder cancer: A review of the evidence. BJUI Compass, 4[1]:5-23 (2023). https://doi.org/10.1002/bco2.186
  4. Jubber I., Rogers Z., Catto J.W., Bottomley S., Glaser A., Downing A., & Absolom K. Sexual Activity, Function and Dysfunction After a Diagnosis of Bladder Cancer. J Sex Med, 19[9]:1431-1441 (2022). doi: 10.1016/j.jsxm.2022.06.016.
  5. Macmillan Cancer Support. Sex life and prostate cancer. Available from: https://www.macmillan.org.uk/cancer-information-and-support/impacts-of-cancer/sex-life-and-prostate-cancer. Last accessed: April 2026
  6. Hyun J.S. Prostate Cancer and Sexual Function. World Journal of Men’s Health, 30[2]:99-107 (2012). https://doi.org/10.5534/wjmh.2012.30.2.99
  7. Zhang, B., Gu, Y., Li, Y., Chen, Y., & Feng, X. Association between overactive bladder and female sexual frequency: a cross-sectional analysis of the National Health and nutrition examination survey data. BMC Women's Health, 25: 84 (2025). https://doi.org/10.1186/s12905-025-03611-8
  8. Przydacz, M., Osman, N., De Cillis, S., Guillot-Tantay, C., Herve, F., Hüsch, T., Illiano, E., Fernandez, A. T., Tutolo, M., Vale, L., Culha, M. G., Cancrini, F., Doizi, S., Geretto, P., Raison, N., Goldman, H. B., Chlosta, P., & Phe, V. Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study. World Journal of Urology, 42(1) (2024). https://doi.org/10.1007/s00345-024-04841-5
  9. Cancer Research UK. Your sex life and what can change it. Available from: https://www.cancerresearchuk.org/about-cancer/coping/physically/sex/sex-life-changes. Last accessed: April 2026
  10. Modh R.A., Mulhall J.P., & Gilbert S.M. Sexual dysfunction after cystectomy and urinary diversion. Nature Reviews Urology, 11[8]:445-53 (2014). doi: 10.1038/nrurol.2014.151.
  11. Macmillan Cancer Support. Vaginal changes, sexual well-being and cancer. Available from: https://www.macmillan.org.uk/cancer-information-and-support/treatment/coping-with-treatment/your-sex-life/vaginal-changes-sexual-well-being. Last accessed: April 2026
  12. Cancer Research UK. Less interest in sex (libido). Available from: https://www.cancerresearchuk.org/about-cancer/prostate-cancer/practical-emotional-support/sex-relationships/less-interest-sex-libido Last accessed: April 2026
  13. Cancer Research UK. Surgery to remove prostate cancer. Available from: https://www.cancerresearchuk.org/about-cancer/prostate-cancer/treatment/surgery/surgery-remove-your-prostate-gland. Last accessed: April 2026
  14. Europa Uomo. Partners express frustration at lost sex life after prostate diagnosis. Available from: https://www.europa-uomo.org/news/partners-express-frustration-at-lost-sex-life-after-prostate-diagnosis/. Last accessed: April 2026
  15. Heiman, J. R. Sexual dysfunction: Overview of prevalence, etiological factors, and treatments. The Journal of Sex Research, 39[1]: 73–78 (2002). https://doi.org/10.1080/00224490209552124
  16. Heyes, S. M., Prior, K. N., Whitehead, D., & Bond, M. J. Toward an Understanding of Patients’ and Their Partners’ Experiences of Bladder Cancer, Cancer Nursing, 43[5]: E254–E263 (2020). https://doi.org/10.1097/ncc.0000000000000718
  17. Kowalkowski M.A., Chandrashekar A., Amiel G.E., Lerner S.P., Wittmann D.A., Latini D.M., & Goltz H.H. Examining sexual dysfunction in non-muscle-invasive bladder cancer: results of cross-sectional mixed-methods research. Sexual Medicine, 2[3]:141-51 (2014). doi: 10.1002/sm2.24
  18. Mohamed N.E., Leung T.M., Benn E.K., Korn T.G., Ali I., Patel D., Gonzalez A., & Quale D.Z. Depression and anxiety among patients treated for bladder cancer: examining clinical, demographic, and psychosocial predictors. American Journal of Clinical and Experimental Urology, 11[5]:401-413 (2023). PMID: 37941645
  19. Prostate Cancer UK. Mental and emotional wellbeing. Prostate Cancer UK. Available from: https://prostatecanceruk.org/prostate-information-and-support/get-support/wellbeing-hub/mental-and-emotional-wellbeing. Last accessed: April 2026
  20. Kinsey D., Pretorius S., Glover L., & Alexander T. The psychological impact of overactive bladder: A systematic review. Journal of Health Psychology, 21[1]:69-81 (2014). doi:10.1177/1359105314522084
  21. Carl, N., Schmidt, L., Büdenbender, B., Blum, A. K., Nientiedt, M., Alpers, G. W., Kriegmair, M. C., & Grüne, B. Body image perception and social support are important predictors of quality of life in bladder cancer patients after cystectomy with urinary diversion. Urologia Internationalis, 108[6]: 556–564 (2024). https://doi.org/10.1159/000541223
  22. Mainwaring J.M., Walker L.M., Robinson J.W., Wassersug R.J. & Wibowo E. The Psychosocial Consequences of Prostate Cancer Treatments on Body Image, Sexuality, and Relationships. Frontiers in Psychology, 12:765315 (2021). doi: 10.3389/fpsyg.2021.765315
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MAT-GB-NON-2025-00406 May 2026